Product ID:DIMETHYL SULFATE
MSDS Date:Jan 24 1989
MSDS Number: EEEFL
Kit Part:=== Responsible Party ===
Company Name:MATHESON TRI-GAS, INC.
Address:959 ROUTE 46 EAST
City:PARSIPPANY
State:NJ
ZIP:07054-0624
Country:US
Info Phone Num:(USA) 973-257-1100, (WHITBY) 905-668-3570, (EDMONTON)
780-471-4036
Chemtrec Ind/Phone:18004249300

Telephone: (USA) 973-257-1100, (WHITBY) 905-668-3570, (EDMONTON)

DIMETHYL SULFATE

CAS: 77-78-1

Fraction By Weight: 100.0%

Reports of Carcinogenicity:NTP:Yes IARC:Yes OSHA:No
Health Hazards Acute and Chronic:INHALATION: SHORT TERM EXPOSURE:
irritation (possibly severe), vomiting, diarrhea, loss of voice,
irregular heartbeat, headache, drowsiness, blindness, bluish skin
color, lung congestion, lung damage, liver damage, paralysis,
convulsions, coma, death LONG TERM EXPOSURE: cancer SKIN CONTACT:
SHORT TERM EXPOSURE: burns, blisters, itching LONG TERM EXPOSURE:
same as effects reported in short term exposure EYE CONTACT: SHORT
TERM EXPOSURE: irritation (possibly severe), tearing LONG TERM
EXPOSURE: same as effects reported in short term exposure
INGESTION: SHORT TERM EXPOSURE: same as effects reported in short
term inhalation, burns LONG TERM EXPOSURE: same as effects reported
in short term exposure
Medical Cond Aggravated by Exposure:

First Aid: INHALATION: If adverse effects occur, remove to
uncontaminated area. Give artificial respiration if not breathing.
If breathing is difficult, oxygen should be administered by
qualified personnel. Get immediate medical attention. SKIN CONTACT:
Wash skin with soap and water for at least 15 minutes while
removing contaminated clothing and shoes. Get immediate medical
attention. Thoroughly clean and dry contaminated clothing and shoes
before reuse. Destroy contaminated shoes. EYE CONTACT: Immediately
flush eyes with plenty of water for at least 15 minutes. Then get
immediate medical attention. INGESTION: Contact local poison
control center or physician immediately. Never make an unconscious
person vomit or drink fluids. Give large amounts of water or milk.
Allow vomiting to occur. When vomiting occurs, keep head lower than
hips to help prevent aspiration. If person is unconscious, turn
head to side. Get medical attention immediately. NOTE TO PHYSICIAN:
For inhalation, consider oxygen. Avoid gastric lavage or emesis.

Flash Point:181 F (83 C) (OC)
Autoignition Temp:370 F (188 C)
Extinguishing Media:regular dry chemical, carbon dioxide, water,
regular foam Large fires: Use regular foam or flood with fine water
spray.
Fire Fighting Procedures:Move container from fire area if it can be
done without risk. Cool containers with water from unmanned hose
holder or monitor nozzles until well after fire is out. Fight large
fires from a protected location or safe distance. Stay away from
the ends of tanks. Dike for later disposal. Do not scatter spilled
material with high-pressure water streams. Water may be used to
blanket fire.
Unusual Fire/Explosion Hazard:Moderate fire hazard. The vapor is
heavier than air. Vapors or gases may ignite at distant ignition
sources and flash back. Vapor/air mixtures are explosive above
flash point.

Neutralizing Agent:

Handling and Storage Precautions:Store and handle in accordance with
all current regulations and standards. Grounding and bonding
required. Notify State Emergency Response Commission for storage or
use at amounts greater than or equal to the TPQ (U.S. EPA SARA
Section 302). SARA Section 303 requires facilities storing a
material with a TPQ to participate in local emergency response
planning (U.S. EPA 40 CFR 355.30). Protect from physical damage.
Store in a cool, dry place. Store in a well-ventilated area. Store
and handle in a detached building. Keep separated from incompatible
substances.
Other Precautions:

Respiratory Protection:The following respirators and maximum use
concentrations are drawn from NIOSH and/or OSHA. At any detectable
concentration - Any self-contained breathing apparatus that has a
full facepiece and is operated in a pressure-demand or other
positive-pressure mode. Any supplied-air respirator with full
facepiece and operated in a pressure-demand or other
positive-pressure mode in combination with a separate escape
supply. Escape - Any air-purifying respirator with a full facepiece
and a canister providing protection against this substance. Any
appropriate escape-type, self-contained breathing apparatus. For
Unknown Concentrations or Immediately Dangerous to Life or Health -
Any supplied-air respirator with full facepiece and operated in a
pressure-demand or other positive-pressure mode in combination with
a separate escape supply. Any self-contained breathing apparatus
with a full facepiece.
Ventilation:Provide local exhaust or process enclosure ventilation
system. Ensure compliance with applicable exposure limits.
Protective Gloves:Wear appropriate chemical resistant gloves.
Eye Protection:Wear splash resistant safety goggles with a faceshield.
Provide an emergency eye wash fountain and quick drench shower in
the immediate work area.
Other Protective Equipment:Wear appropriate chemical resistant
clothing.
Supplemental Safety and Health
DIMETHYL SULFATE: 1 ppm (5 mg/m3) OSHA TWA (skin) 0.1 ppm (0.5 mg/m3)
OSHA TWA (skin) (vacated by 58 FR 35338, June 30, 1993) 0.1 ppm
ACGIH TWA (skin) 0.1 ppm (0.5 mg/m3) NIOSH recommended TWA 10
hour(s) (skin)

Boiling Pt:Not available
Melt/Freeze Pt:-26 F (-32 C)
Vapor Pres:0.5 mmHg @ 20 C
Vapor Density:4.35
Spec Gravity:1.333
pH:Not available
Evaporation Rate & Reference:Not available
Solubility in Water:2.8% @ 18 C
Appearance and Odor:PHYSICAL STATE:liquid COLOR:colorless TEXTURE:oily
ODOR:faint odor, onion odor
Corrosion Rate:

Stability Indicator/Materials to Avoid:Contact with water or moist air
may form flammable and/or toxic gases or vapors.
Stability Condition to Avoid:Avoid heat, flames, sparks and other
sources of ignition. Containers may rupture or explode if exposed
to heat. Dangerous gases may accumulate in confined spaces. Keep
out of water supplies and sewers.
Hazardous Decomposition Products:Thermal decomposition products: oxides
of sulfur, carbon Thermal decomposition products: oxides of sulfur,
carbon
Conditions to Avoid Polymerization:Will not polymerize.

Waste Disposal Methods:Subject to disposal regulations: U.S. EPA 40 CFR
262. Hazardous Waste Number(s): U103. Dispose in accordance with
all applicable regulations.

Toxicological Information:DIMETHYL SULFATE: IRRITATION DATA: 10 mg/24
hour(s) open skin-rabbit severe; 100 mg/4 second(s) rinsed
eyes-rabbit severe; 50 ug/24 hour(s) eyes-rabbit severe TOXICITY
DATA: 45 mg/m3/4 hour(s) inhalation-rat LC50; 205 mg/kg oral-rat
LD50 CARCINOGEN STATUS: NTP: Anticipated Human Carcinogen; IARC:
Human Inadequate Evidence, Animal Sufficient Evidence, Group 2A;
ACGIH: A3 -Animal Carcinogen; EC: Category 2 LOCAL EFFECTS:
Corrosive: inhalation, skin, eye, ingestion ACUTE TOXICITY LEVEL:
Highly Toxic: inhalation Toxic: ingestion MEDICAL CONDITIONS
AGGRAVATED BY EXPOSURE: respiratory disorders TUMORIGENIC DATA:
Available. MUTAGENIC DATA: Available. REPRODUCTIVE EFFECTS DATA:
Available.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:ECOTOXICITY DATA: FISH TOXICITY: 7500 ug/L 96 hour(s) LC50
(Mortality) Bluegill (Lepomis macrochirus) ALGAL TOXICITY: 1300000
ug/L 0.25 week(s) (Cytogenetic) Blue-green algae (Anabaena
variabilis) ENVIRONMENTAL SUMMARY: Toxic to aquatic life.

Transport Information:U.S. DOT 49 CFR 172.101: PROPER SHIPPING NAME:
Dimethyl sulfate ID NUMBER: UN1595 HAZARD CLASS OR DIVISION: 6.1
PACKING GROUP: I LABELING REQUIREMENTS: Poison; Corrosive QUANTITY
LIMITATIONS: PASSENGER AIRCRAFT OR RAILCAR: Forbidden CARGO
AIRCRAFT ONLY: Forbidden

SARA Title III Information: SARA TITLE III SECTION 302 EXTREMELY
HAZARDOUS SUBSTANCES (40 CFR 355.30): Dimethyl sulfate: 500LBSTPQ
SARA TITLE III SECTION 304 EXTREMELY HAZARDOUS SUBSTANCES (40 CFR
355.40): Dimethyl sulfate: 100LBSRQ SARA TITLE III SARA SECTIONS
311/312 HAZARDOUS CATEGORIES (40 CFR 370.21): ACUTE: Yes
CHRONIC: Yes FIRE: Yes REACTIVE: No SUDDEN RELEASE: No SARA
TITLE III SECTION 313 (40 CFR 372.65): Dimethyl sulfate
Federal Regulatory Information:CERCLA SECTIONS 102a/103 HAZARDOUS
SUBSTANCES (40 CFR 302.4): Dimethyl sulfate: 100LBSRQ OSHA PROCESS
SAFETY (29CFR1910.119): Not regulated.
State Regulatory Information: California Proposition 65: Known to the
state of California to cause the following: Dimethyl sulfate Cancer
(Jan 01, 1988)